Bremelanotide (PT141)

Name	Bremelanotide (PT141)
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
CAS	32780-32-8
Sequence
Molecular Weight	1025.2
Purity (HPLC)	99%min
Appearance	White powder
Single Impurity(HPLC)	1%max
Amino Acid Composition	±10% of theoretical
Peptide Content(N%)	≥80.0%
Water Content(KF)	≤6.0%
Acetate Content(HPLC)	≤15%
MS(ESI)	Consistent
Mass Balance	95.0~105.0%
PT141 (Bremelanotide) is a cyclic hepta-peptide lactam analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the melanocortin receptors MC3-R and MC4-R in the central nervous system. It is the generic term for a new medication for use in treating sexual dysfunction in men (erectile dysfunction or impotence) as well as sexual dysfunction in women (sexual arousal disorder). It is a synthetic aphrodisiac. Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire.

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Peptide